Research is an integral part of BPEF to pioneer innovations and conducts implementation research. A qualified team of Researchers and leadership committed to expanding the frontiers of knowledge and, more importantly, its application. 

BPEF has conducted many health researches. It has key personnel to implement the project with many years of experience in eye care including xerophthalmia for children's eye care subsequently scaled up to cover the whole population of the country, Seasonal hyperacute panuveitis-1984 a destructive eye disease is seen only in Nepal, Causes of Blindness and Visual Impairment among Students in Integrated Schools for the Blind in Nepal, Optical Needs of Students with Low Vision in Integrated Schools of Nepal, student-led screening for vision defects through a scientific study.

Published Articles

1. Corneal blindness: a global perspective (PMID:11285665)
2. Epidemiologic Characteristics, Predisposing Factors, and Etiologic Diagnosis of Corneal Ulceration in Nepal (
3. Prevention of Corneal Ulceration in the Developing World (
4. Corneal ulceration in south-east Asia III: prevention of fungal keratitis at the village level in south India using topical antibiotics (
6. Corneal ulceration in South East Asia. II: A strategy for the prevention of fungal keratitis at the village level in Burma (
7. The South Asian Cataract Management Study: complications, vision outcomes, and corneal endothelial cell loss in a randomized multicenter clinical trial comparing intracapsular cataract extraction with and without anterior chamber intraocular lens implantation ( 
8. Effect of intestinal helminth infection on retinol and β-carotene status among rural Nepalese (
9. Microbial Keratitis in the Developing World: Does Prevention Work? (
10. Keratitis due to Aspergillus flavus successfully treated with thiabendazole. (
11. Toxoplasma infection in selected patients in Kathmandu, Nepal. ((PMID:15024774))
12. Do non-communicable diseases such as hypertension and diabetes associate with primary open-angle glaucoma? Insights from a case–control study in Nepal (
13. Causes of Blindness and Visual Impairment among Students in Integrated Schools for the Blind in Nepal(
14. Seroepidemiological study of Toxoplasma infection in central and western regions in Nepal (
15. Managing corneal disease: focus on suppurative keratitis (PMID: 20212926)
17. Diagnosing and managing microbial keratitis (PMID: 26435583)
18. SHAPU: Forty years on Mystery Persists (
19. Seasonal Hyperacute Panuveitis in Nepal: A Review over 40 Years of Surveillance (
20. Youngest reported Seasonal Hyperacute Panuveitis case (
21. SHAPU - Seasonal Hyperacute PanUveitis (
22. Village-Integrated Eye Worker trial (VIEW): rationale and design of a cluster-randomised trial to prevent corneal ulcers in resource-limited settings (
23. Optical Needs of Students with Low Vision in Integrated Schools of Nepal (doi: 10.1097/OPX.0b013e3182772f3c)
24. Utilization of primary eye health services by people from a rural community of Nepal (
25. Ocular morbidity among porters at high altitudes (
26. Student-led screening of school children for refractive error correction (

Ongoing Research Projects

1. Prof. Madan Prasad Upadhyay: Microbial Etiology Analysis Using Polymerase Chain Reaction Test & Whole Genomic Sequencing In Cases Of Seasonal Hyperacute Panuveitis (SHAPU)
2. Prof. Madan Prasad Upadhyay: Opportunistic screening of Blood pressure, Intra-ocular Pressure and Obesity in tertiary level Eye ENT hospital at Bhaktapur, Nepal
3. Dr. Barsha Suwal (Prediction of visual acuity and need for early treatment from changes in spectral domain OCT in patients with center serous chorio-retinopathy
4. Dr. Sanjib Kumar Upadhyay: Infant Hearing Screening at selected Immunization centers of Kathmandu Valley
5. Mr. Rajan Shrestha: Study of co-morbidities of cataract and visual outcome of patients after cataract surgery
6. Mr. Rajan Shrestha: Physical activity, knowledge and its behavioral intention among patients visiting tertiary eye hospital, Bhaktapur
7. Dr. Nirsara Shrestha: Clinical and epidemiological study in patients with glaucoma in tertiary eye care center, Bhaktapur
8. Dr. Barsha Suwal: Practice pattern for the management of acute post-operative endophthalmitis at a tertiary eye hospital in Nepal
9. Rajan Shrestha: Anxiety, Depression and Functional impairment during COVID-19 Pandemic among employees of Hospital for Children Eye ENT and Rehabilitation Services, Bhaktapur

Proposed Research Projects

1. Mr. Bijay Khatri: Noise Pollution in Kathmandu Valley
2. Dr. Nirsara Shrestha: Visual outcome among patients with primary open angle glaucoma in tertiary eye care center – 5 year longitudinal study
3. Mr. Janak Bhattarai: Prevalence of vision and hearing problems among traffic police
4. Rajan Shrestha: Status of Healthy work-site culture in Hospital for Children, Eye ENT and Rehabilitation Services, Bhaktapur
5. Rajan Shrestha: Cost effectiveness of student led vision screening for refractive error correction in school children in Changunarayan Municipality, Nepal
6. Rajan Shrestha: Compliance of Spectacles Use and Eye Health Service Utilization among School Children of Province 3, Nepal
7. Dr. Nirsara Shrestha: Glaucoma among family members of primary open angle glaucoma in Bhaktapur
8. Dr. Arjun Shrestha: Indications and visual outcome of intravitreal Bevacizumab in patients with retinal diseases in Hospital for Children Eye ENT and Rehabilitation Services, Bhaktapur: A retrospective Study
9. Dr. Arjun Shrestha: Diabetic Retinopathy among patients with diabetes attending Hospital for Children Eye ENT and Rehabilitation Services, Bhaktapur
10. Bijay Khatri: Opportunistic screening of Glycemia
11. Dr. Luna Mathema: Endoscopic transcanal myringoplast butterfly vs modified butterfly in graft uptake and hearing outcome